中国科学院心理研究...

电脑版
提示:原网页已由神马搜索转码, 内容由sourcedb.psych.cas.cn提供.
» 您的位置:首页 > 中文 > 心理所论文库
论文编号:
第一作者所在部门:
中文论文题目:
Rumination and the default mode network: Meta-analysis of brain imaging studies and implications for depression
英文论文题目:
Rumination and the default mode network: Meta-analysis of brain imaging studies and implications for depression
论文题目英文:
作者:
Zhou, Hui-Xia
论文出处:
刊物名称:
NEUROIMAGE
年:
2020
卷:
206
期:
0
页:
9
联系作者:
Yan, Chao-Gan
收录类别:
影响因子:
5.812
摘要:

Rumination is strongly and consistently correlated with depression. Although multiple studies have explored the neural correlates of rumination, findings have been inconsistent and the mechanisms underlying rumination remain elusive. Functional brain imaging studies have identified areas in the default mode network (DMN) that appear to be critically involved in ruminative processes. However, a meta-analysis to synthesize the findings of brain regions underlying rumination is currently lacking. Here, we conducted a meta-analysis consisting of experimental tasks that investigate rumination by using Signed Differential Mapping of 14 fMRI studies comprising 286 healthy participants. Furthermore, rather than treat the DMN as a unitary network, we examined the contribution of three DMN subsystems to rumination. Results confirm the suspected association between rumination and DMN activation, specifically implicating the DMN core regions and the dorsal medial prefrontal cortex subsystem. Based on these findings, we suggest a hypothesis of how DMN regions support rumination and present the implications of this model for treating major depressive disorder characterized by rumination.

英文摘要:
外单位作者单位:
备注: